PRANK (SOAP)

By | September 22, 2011

PRANK is a probabilistic multiple alignment program for DNA, codon and amino-acid sequences. It’s based on a novel algorithm that treats insertions correctly and avoids over-estimation of the number of deletion events. In addition, PRANK borrows ideas from maximum likelihood methods used in phylogenetics and correctly takes into account the evolutionary distances between sequences. Lastly, PRANK allows for defining a potential structure for sequences to be aligned and then, simultaneously with the alignment, predicts the locations of structural units in the sequences.

Name
PRANK (SOAP)
Documentation
http://www.ebi.ac.uk/Tools/webservices/services/msa/prank_soap
Protocol
SOAP
WSDL
Endpoint
http://www.ebi.ac.uk/Tools/services/soap/prank
Topic
Nucleotide Multiple Alignment, Protein Multiple Alignment
Type
Analysis
Tags
, , , , ,
Description

PRANK is a probabilistic multiple alignment program for DNA, codon and amino-acid sequences. It’s based on a novel algorithm that [...]

Further information

PRANK is a probabilistic multiple alignment program for DNA, codon and amino-acid sequences. It’s based on a novel algorithm that treats insertions correctly and avoids over-estimation of the number of deletion events. In addition, PRANK borrows ideas from maximum likelihood methods used in phylogenetics and correctly takes into account the evolutionary distances between sequences. Lastly, PRANK allows for defining a potential structure for sequences to be aligned and then, simultaneously with the alignment, predicts the locations of structural units in the sequences.

Original source
BioCatalogue

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